Sublingual immunother­apy (SLIT) has been used in human med­i­cine with good suc­cess for aller­gic rhini­tis and asthma. More recently ben­e­fi­cial effects have been reported for atopic der­mati­tis.  An advan­tage of SLIT is ease of admin­is­tra­tion and tol­er­a­bil­ity. Lim­ited stud­ies exist in vet­eri­nary med­i­cine. The pur­pose of the present study was to eval­u­ate safety and effi­cacy of SLIT in an exper­i­men­tal model for canine atopic dermatitis.

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2. Specific sublingual immunotherapy in atopic dermatitis. Results of a 6-year follow-up of 35 consecutive patients. Allergol Immonopathol (Madr). 2000 Mar-Apr;28(2):54-62. Mastrandrea F, Serio G, Minelli M, Minardi A, Scarcia G, Coradduzza G, Parmiani S.

3. Sublingual immunotherapy in mite-sensitized children with atopic dermatitis: A randomized, double-blind, placebo-controlled study. The Journal of Allergy and Clinical Immunology, Volume 120, Issue 1, Pages 164-170, July 2007. Giovanni B. Pajno, MD, Lucia Caminiti, MD, Daniela Vita, MD, Giovanni Barberio, MD, Giuseppina Salzano, MD, Fortunato Lombardo, MD, Giorgio Walter Canonica, MD, Giovanni Passalacqua, MD.

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